Current

Association between plausible genetic factors and weight loss from GLP1-RA and bariatric surgery

Abstract Obesity is a major public health challenge. Glucagon-like peptide-1 receptor agonists (GLP1-RA) and bariatric surgery (BS) are effective weight loss interventions; however, the genetic factors influencing treatment response remain largely unexplored. Moreover, most previous studies have focused on race and ethnicity rather than genetic ancestry. Here we analyzed 10,960 individuals from 9 multiancestry biobank […]

Association between plausible genetic factors and weight loss from GLP1-RA and bariatric surgery Read More »

Utilizing Low-Intensity Light Therapy to Promote Healing and Alleviate Post-Surgical Pain

Review Utilizing Low-Intensity Light Therapy to Promote Healing and Alleviate Post-Surgical Pain: A Comprehensive Systematic Review and Meta-Analysis Natália de Lima Melo b, Marcio Silva dos Santos Junior c, Aline Pinto Monteiro Costa Sousa d, Elisângela de Lavor Farias e b Master in Health Sciences from the Faculdade de Medicina do ABC (FMABC) in the

Utilizing Low-Intensity Light Therapy to Promote Healing and Alleviate Post-Surgical Pain Read More »

Selective remodelling of the adipose niche in obesity and weight loss

Abstract Weight loss significantly improves metabolic and cardiovascular health in people with obesity1,2,3. The remodelling of adipose tissue (AT) is central to these varied and important clinical effects4. However, surprisingly little is known about the underlying mechanisms, presenting a barrier to treatment advances. Here we report a spatially resolved single-nucleus atlas (comprising 171,247 cells from 70

Selective remodelling of the adipose niche in obesity and weight loss Read More »

Polygenic prediction of body mass index and obesity through the life course and across ancestries

Abstract Polygenic scores (PGSs) for body mass index (BMI) may guide early prevention and targeted treatment of obesity. Using genetic data from up to 5.1 million people (4.6% African ancestry, 14.4% American ancestry, 8.4% East Asian ancestry, 71.1% European ancestry and 1.5% South Asian ancestry) from the GIANT consortium and 23andMe, Inc., we developed ancestry-specific

Polygenic prediction of body mass index and obesity through the life course and across ancestries Read More »

Clinical Effects of Probiotics Across Health Conditions: An Umbrella Review of Systematic Reviews and Meta-Analyses

Review Clinical Effects of Probiotics Across Health Conditions: An Umbrella Review of Systematic Reviews and Meta-Analyses Rafaela Nonato de Menezes a,*, Heloísa Lima Silva a, Maysa de Oliveira Barbosa b,c, Maria Neyze Martins Fernandesb, Ernandes Costa Linbraim d, Danilo Ferreira de Sousa e a Department of Nutrition, Centro Universitário de Juazeiro do Norte (UNIJUAZEIRO), Juazeiro

Clinical Effects of Probiotics Across Health Conditions: An Umbrella Review of Systematic Reviews and Meta-Analyses Read More »

Effectiveness of Low-Intensity Light Therapy in the Control of Pain and Healing

Review Effectiveness of Low-Intensity Light Therapy in the Control of Pain and Healing: An Umbrella Review with Meta-Analysis Felipe Gurgel do Amaral Mota b, Gustavo Oliveira Marianno c, Uilna Natércia Soares Feitosa Pedro d, Sabrina Martins Alves e ARTICLE INFOEdited by Dr G LiuKeywords:Low-Level Light TherapyPostoperative PainWound HealingPhototherapy Highlights ABSTRACT This umbrella review with meta-analysis

Effectiveness of Low-Intensity Light Therapy in the Control of Pain and Healing Read More »